Computational chemistry on demand

Get the answer, not a software project.

You have a chemistry question — which analog is more reactive, why two molecules bind, what a spectrum means. We run the quantum chemistry and hand you a clear, figure-rich report with the data behind it. No cluster to set up, no scripts to learn, no software to install. Run by a PhD computational chemist on our own validated engine.

Confidential by default · NDA on request · your structures never leave a private environment.

Who it's for

For teams who need the chemistry, not the headache

Small biotech and chemical R&D teams, medicinal chemists, and academic labs without an in-house computational specialist. When you need a quantum-chemistry answer for a decision — a synthesis route, an analog choice, a structure confirmation — but don't want to hire a comp-chem team or learn a heavyweight package, you hand it to us.

You get a report, not a log file

A concise PDF with the question, the method, the figures, the interpretation, and a plain-language conclusion — plus the raw output and structures so your team can reproduce or extend it.

Confidential & on-premise

Calculations run in a private environment — nothing is sent to a public cloud. Your IP and structures stay yours. NDA signed on request before you share anything.

Run by a domain expert

Every project is run and interpreted by a PhD computational chemist — not a black box. You get judgment on method choice and on what the numbers do and don't mean. Meet the chemist →

Service packages

Three things we deliver best

Fixed-scope starting points below — most projects are quoted to fit. Each links to a worked, real-data example from our blog so you can see exactly the kind of output you'd receive.

Reactivity & metabolic-site profiling
from €690
  • Frontier orbitals (HOMO/LUMO), electrophilicity index ω, Fukui / reactive-site maps
  • Covalent-warhead tuning & ranking across a series
  • Likely metabolic soft-spots (oxidation-prone sites)
  • Substituent / electronic effects (Hammett-style trends)
  • Deliverable: report + figures + data · 3–5 working days
See a worked example →
Spectra & photophysics
from €1,500
  • IR / Raman vibrational spectra & assignment
  • UV-Vis / excited states (TDDFT), photoswitch behaviour
  • GIAO NMR shieldings for structure confirmation
  • Triplets, spin-orbit coupling & phosphorescence (specialist)
  • Deliverable: report + simulated spectra + data · 5–10 working days
See a worked example →

Series, screening campaigns and ongoing work are quoted per project. Advisory / method-review available at a day rate; monthly retainers from €1,500/month for teams with recurring questions. Tell us your problem for a fixed quote.

Also available

The full toolbox, on request

Beyond the three packages, the same engine and expertise cover a wide range of molecular questions.

Structure & energetics

Geometry optimization & conformer ensembles · reaction thermochemistry (ΔG, barriers, rates) · tautomer & protonation-state ranking · relative stability across analogs · implicit-solvent (C-PCM) energetics · atomic charges (ESP / Mulliken / Löwdin) and electrostatic-potential maps.

Bonding & visualization

QTAIM topology (bond / ring / cage critical points) · orbital & electron-density maps for figures and talks · ESP-mapped molecular surfaces · σ-hole / halogen-bond analysis · publication-ready 3D renders and plots · method selection & second-opinion review on existing calculations.

How it works

From your question to your answer in three steps

1

Tell us the question

Send the structures (SMILES, a sketch, or a file) and what you're trying to decide. We reply with a clear scope, method, price and timeline — and sign an NDA first if you prefer.

2

We run the chemistry

We run the calculations on our own validated engine in a private environment, choosing the right method and basis for the question — and sanity-check the results before they reach you.

3

You get a clear report

A concise, figure-rich report with the conclusion in plain language, plus all raw data and structures. One round of follow-up questions included.

Honesty first

We tell you what quantum chemistry can and can't answer for your case before you pay. Many questions — relative reactivity, interaction strength, which form dominates, spectral assignment — are answered well and robustly. Some absolute numbers (e.g. absolute pKa, exact UV-Vis band positions) carry known systematic offsets; where that's true we say so up front and frame the result as a ranking or trend rather than a bench-matched single value. The underlying engine reproduces reference Hartree-Fock energies to ~1e-10 Hartree and is cross-checked against established codes — but our job is to give you a defensible answer to your decision, not a number without a caveat.

Have a molecule on your desk right now?

Send it over. We'll tell you whether quantum chemistry can answer your question — and give you a fixed quote — before you commit to anything.